Témakiírások
Extracellular vesicles combined with self-assembled peptide nanotubes for reconstruction of neuron-neuron interactions
témakiírás címe
Extracellular vesicles combined with self-assembled peptide nanotubes for reconstruction of neuron-neuron interactions
intézmény
doktori iskola
témakiíró
tudományág
témakiírás leírása
The Biomolecular Self-assembly “Momentum” research group is looking for a PhD/Post-doc student to conduct experimental work addressing the isolation and biophysical characterisation of different types of extracellular vesicles (EVs) and explore their potential in neuroregeneration when combined with scaffold-forming peptide nanotubes. EVs are biological nanoparticles released by cells into the extracellular space and contain biomolecules on their external surface that has roles in extracellular matrix formation. They are also important mediators of intracellular communication and are involved in many physiological conditions, providing a wealth of information for early diagnosis and treatment of diseases.
The successful applicant will apply the modern isolation and detection techniques including various spectroscopic, scattering and imaging methods, proteomic and lipidomic analysis, mRNA isolation addressing their structure and morphology.
RCNS is a new highly competitive research center aiming to be one of the leading institutes in natural sciences. The Centre provides a stimulating environment due to a wide range of researches with a significant number of them conducting BSc, MSc, PhD or Post-Doc programs. The Biomolecular Self-assembly “Momentum” research group, co-funder of the Biological Soft Matter Platform, is located at the Institute of Materials Chemistry, where the applicant will have access to a state of the art infrastructure. The Biological Soft Matter Platform coordinates several major Academy-Industry programs focusing on EVs, exosomes and membrane active biomolecules, where the successful candidate will have the possibility to spend secondments and gain experience in the private sector as well. The group is closely collaborating with experts of the field from the Institute of Enzymology, Semmelweis University as well as Eötvös Loránd University where access to a wide range of further techniques is granted. The current position also involves a daily interaction with collaborating industrial partners, allowing the successful candidate to acquire joint academic and private experience.
Related references from the group:
T Sonallya et al.: Categorizing interaction modes of antimicrobial peptides with extracellular vesicles: Disruption, membrane trespassing, and clearance of the protein corona, Journal of Colloid and Interface Science 679, 496-509
P Singh et al. Removal and identification of external protein corona members from RBC‐derived extracellular vesicles by surface manipulating antimicrobial peptides
Journal of Extracellular Biology 2 (3), e78
For further information, please visit ttk.hu or bionano.ttk.hu.
Candidates should send CV and short motivation letter to the group leader Tamás Beke-Somfai (beke-somfai.tamas@ttk.hu). For further information or informal enquiries, please contact Tamás Beke-Somfai either via email or phone +36-1-3826-689.
The successful applicant will apply the modern isolation and detection techniques including various spectroscopic, scattering and imaging methods, proteomic and lipidomic analysis, mRNA isolation addressing their structure and morphology.
RCNS is a new highly competitive research center aiming to be one of the leading institutes in natural sciences. The Centre provides a stimulating environment due to a wide range of researches with a significant number of them conducting BSc, MSc, PhD or Post-Doc programs. The Biomolecular Self-assembly “Momentum” research group, co-funder of the Biological Soft Matter Platform, is located at the Institute of Materials Chemistry, where the applicant will have access to a state of the art infrastructure. The Biological Soft Matter Platform coordinates several major Academy-Industry programs focusing on EVs, exosomes and membrane active biomolecules, where the successful candidate will have the possibility to spend secondments and gain experience in the private sector as well. The group is closely collaborating with experts of the field from the Institute of Enzymology, Semmelweis University as well as Eötvös Loránd University where access to a wide range of further techniques is granted. The current position also involves a daily interaction with collaborating industrial partners, allowing the successful candidate to acquire joint academic and private experience.
Related references from the group:
T Sonallya et al.: Categorizing interaction modes of antimicrobial peptides with extracellular vesicles: Disruption, membrane trespassing, and clearance of the protein corona, Journal of Colloid and Interface Science 679, 496-509
P Singh et al. Removal and identification of external protein corona members from RBC‐derived extracellular vesicles by surface manipulating antimicrobial peptides
Journal of Extracellular Biology 2 (3), e78
For further information, please visit ttk.hu or bionano.ttk.hu.
Candidates should send CV and short motivation letter to the group leader Tamás Beke-Somfai (beke-somfai.tamas@ttk.hu). For further information or informal enquiries, please contact Tamás Beke-Somfai either via email or phone +36-1-3826-689.
felvehető hallgatók száma
1 fő
helyszín
Institute of Materials and Environmental Chemistry
Research Centre For Natural Sciences
H-1117 Magyar tudósok körútja 2., Budapest, Hungary
jelentkezési határidő
2026-05-31