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Thesis topic proposal
 
Csaba Vágvölgyi
Tamás Papp
Genetic background of the terpene biosynthesis in zygomycetes fungi

THESIS TOPIC PROPOSAL

Institute: University of Szeged
biology
Doctoral School of Biology

Thesis supervisor: Tamás Papp
co-supervisor: Csaba Vágvölgyi
Location of studies (in Hungarian): SZTE TTIK, Mikrobiológiai T
Abbreviation of location of studies: SZTE


Description of the research topic:

Fungal terpenoid metabolites, such as the membrane contituent ergosterol, prenyl groups of certain proteins or the ubiquinone and carotenoids, are synthesized via the common mevalonate-isoprenoid pathway. Activity of the central enzymes and the encoding genes therefore affect so important biological processes as the maintenance of the membrane structure, susceptibility to different antifungal agents, morphogenesis, dimorphism, adaptation to the environmental changes, or production of certain metabolites (e.g. carotenoids). Functional analysis of the key genes and examination of their regulation are planned. The study includes the modification of the pathway and the analysis of the metabolite production and morphogenesis of the fungi in this system.

Required language skills: angol
Number of students who can be accepted: 1

Deadline for application: 2015-10-13


2024. IV. 17.
ODT ülés
Az ODT következő ülésére 2024. június 14-én, pénteken 10.00 órakor kerül sor a Semmelweis Egyetem Szenátusi termében (Bp. Üllői út 26. I. emelet).

 
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