ODT - THESIS TOPIC: Márton Tamás Tóth: Complex clinicopathological investigation of ...


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Thesis topic proposal

Complex clinicopathological investigation of human temporal lobe epilepsy

THESIS TOPIC PROPOSAL

Institute: University of Pécs
clinical medicine
Doctoral School of Clinical Neurosciences

Thesis supervisor: Márton Tamás Tóth
co-supervisor: Endre Pál
Location of studies (in Hungarian): PTE ÁOK
Abbreviation of location of studies: ÁOK

Description of the research topic:

The aim of the study is to review retrospectively the database of patients of the Department of Neurology, University of Pécs who underwent temporal lobe epilepsy surgery, and to record the clinical data of patients undergoing surgery in a prospective manner.During the evaluation of clinical data, especially regarding with seizure reduction and cognitive changes after surgery. Tissue samples removed during surgery will be (re-)evaluated, especially for the extent and nature of hippocampal damage.We are developing a scoring system to quantify the level of damage.Detailed immunohistochemical and in situ hybridization techniques are used to examine which cell groups are damaged and to what extent, and then the neuropathological data will be correlated with the clinical data.

Number of students who can be accepted: 1

Deadline for application: 2024-05-16

2024. IV. 17.
ODT ülés
Az ODT következő ülésére 2024. június 14-én, pénteken 10.00 órakor kerül sor a Semmelweis Egyetem Szenátusi termében (Bp. Üllői út 26. I. emelet).