Thesis supervisor: Hajnalka Laczkó-Dobos
Location of studies (in Hungarian): Biological Research Centre, Institute of Genetics, Lysosomal Degradation Research Group Abbreviation of location of studies: SZBK
Description of the research topic:
Autophagy is the so-called "self-eating" process of cells which always works at a basic level, but can be enhanced by certain stress responses, such as starvation. Autophagy is not only important for surviving stress, but also for maintaining cell homeostasis. Defective autophagy can lead to neurological disorders (such as Parkinson's disease, Alzheimer's disease, and Huntington's disease), aging, and cancer. Substances intended for degradation are packaged in cell organelles surrounded by membranes and are broken down with the help of lysosomes and finally reused. In our study, we want to reveal how the main components of these autophagic membranes, lipids and autophagic proteins, interact and help each other. To answer this question, we use several human cell lines as models, as well as biochemical, biophysical and cell biological methods.
Required language skills: English Further requirements: Interest in biochemical and cell biological methods
Number of students who can be accepted: 2
Deadline for application: 2023-09-01
2024. IV. 17. ODT ülés Az ODT következő ülésére 2024. június 14-én, pénteken 10.00 órakor kerül sor a Semmelweis Egyetem Szenátusi termében (Bp. Üllői út 26. I. emelet).
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