ODT - THESIS TOPIC: Erzsébet Toldy: Relationship between gestational diabetes ...


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Thesis topic proposal

Relationship between gestational diabetes mellitus and thyroid function consideration by vitamin D supply

THESIS TOPIC PROPOSAL

Institute: University of Pécs
clinical medicine
Doctoral School of Clinical Medicine

Thesis supervisor: Erzsébet Toldy
Location of studies (in Hungarian): PTE ÁOK Pésc, Szigeti u 12.
Abbreviation of location of studies: ÁOK

Description of the research topic:

The prevalence of gestational diabetes mellitus (GDM) in the past 15 years is held 5,3-9,3% based on Hungarian data. Thyroid dysfunction (TD) recognized during pregnancy occurs in 1-3%. It is well-known that vitamin D influences the glucose homeostasis and several authors reported the relationship between TD and vitamin D deficiency. The aim of the study is to investigate the effects examined commonly and separately of GDM and TD on pregnancy, delivery and new-born outcomes. We determine the free T3/T4 and total T3/T4 ratio in order to evaluate whether the conversion of T4-T3 in GDM differs from GDM-negative cases and whether this process is influenced by the serum level of 25(OH)D. Furthermore, we study which is the fraction of vitamin D that reflects the vitamin D supply of the pregnant women the most reliably: total 25(H)D, direct measured free 25(OH)D or free 25(OH)D calculated by binding proteins.

Number of students who can be accepted: 1

Deadline for application: 2023-05-19

2024. IV. 17.
ODT ülés
Az ODT következő ülésére 2024. június 14-én, pénteken 10.00 órakor kerül sor a Semmelweis Egyetem Szenátusi termében (Bp. Üllői út 26. I. emelet).