ODT - THESIS TOPIC: István Kiss: Role of genetic polymorphisms ...


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Thesis topic proposal

Role of genetic polymorphisms in cancer susceptibility

THESIS TOPIC PROPOSAL

Institute: University of Pécs
clinical medicine
Doctoral School of Clinical Medicine

Thesis supervisor: István Kiss
Location of studies (in Hungarian): PTE ÁOK Szigeti u. 12.
Abbreviation of location of studies: ÁOK

Description of the research topic:

The so called individual susceptibility factors play an important role in determining the risk of chronic non infectious diseases. These are typically single nucleotide polymorphisms on the area of genes related to cancer development. They are not inherited mutations, but rather normal gene variants, which, however, to a certain extent have an influence on the risk of the formation of different tumours.
In the framework of this PhD topic, allelic distributions (e.g. genes of metabolizing enzymes, DNA repair genes, tumour suppressor genes) are compared between cancer patients and cancer free controls. These molecular epidemiological studies (case-control studies) can lead to the identification of genetic risk factors of certain tumours.

Number of students who can be accepted: 1

Deadline for application: 2023-05-19

2024. IV. 17.
ODT ülés
Az ODT következő ülésére 2024. június 14-én, pénteken 10.00 órakor kerül sor a Semmelweis Egyetem Szenátusi termében (Bp. Üllői út 26. I. emelet).