The agressive behaviour and dismal prognosis of pancreatic cancer is well-known. However more advantageous survival can be achieved by the early diagnosis. Such supporting screening method would be of especially great importance. Promising researches are going on in the field of micro-RNS expression and K-ras gene mutation analysis, which may have pathognomic value. However their clinical relevance and applicability as biomarker are still unsolved. In this setting examination of pancreatic tumor tissue and blood samples would supply useful data. The researches would be performed in collaboration with the Department of Public Health Medicine.