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Thesis topic proposal
 
High-throughput screening for DNA damage response profiling

THESIS TOPIC PROPOSAL

Institute: University of Szeged
biology
Doctoral School of Biology

Thesis supervisor: Szilvia Juhász
co-supervisor: Máté Manczinger
Location of studies (in Hungarian): Biological Research Centre of Szeged
Abbreviation of location of studies: SzBK


Description of the research topic:

In oncology, comprehensive omics and functional enrichment studies have led to extensive profiling of genetic changes in molecular pathways that can be attributed to the clinical phenotype of the tumor mass. Consequently, molecular pathway-based therapeutic interventions are prominent in different types of cancer. In line with this, the main achievement of modern oncology is that the efficient treatment is coupled with deep-molecular analysis. The proposed PhD project focuses on the high-troughput screening of DNA repair deficient tumor cells applying DNA damage respone monitoring systems in combination with deep sequencing.

Required language skills: English
Further requirements: 
Strong background in molecular cell biology.

Number of students who can be accepted: 1

Deadline for application: 2022-12-31


2024. IV. 17.
ODT ülés
Az ODT következő ülésére 2024. június 14-én, pénteken 10.00 órakor kerül sor a Semmelweis Egyetem Szenátusi termében (Bp. Üllői út 26. I. emelet).

 
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