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Thesis topic proposal
 
Isolation and genetic modification of bacterial viruses to effectively treat nosocomial, antibiotic resistant pathogenic species

THESIS TOPIC PROPOSAL

Institute: University of Szeged
biology
Doctoral School of Biology

Thesis supervisor: Bálint Kintses
Location of studies (in Hungarian): Biological Research Centre, Szeged; 6726 Szeged, Temesvári krt. 62
Abbreviation of location of studies: SZBK


Description of the research topic:

The rapid spread of antibiotic resistant pathogens represents a dire healthcare threat. Due to the alarmingly quick decrease of the efficiency of novel and current antibiotics, there is an urgent need for effective alternitves. One of the most promising avenues is the therapeutic application of bacterial viruses (bacteriophages or phages). During the course of the doctoral program, the PhD student will explore the therapeutic applicability of phages isolated from the environment against a panel of antibiotic resistant bacterial species. Following comprehensive bioinformatical and molecular biological analysis, the possibility of employing genome engineering technologies is assessed. The observations will ultimately augment the therapeutic potential of phage based treatments for widespread usage.

Required language skills: English
Further requirements: 
-basic molecular biology techniques
-motivation
-reading and interpreting of scientific literature

Number of students who can be accepted: 1

Deadline for application: 2021-12-31


2024. IV. 17.
ODT ülés
Az ODT következő ülésére 2024. június 14-én, pénteken 10.00 órakor kerül sor a Semmelweis Egyetem Szenátusi termében (Bp. Üllői út 26. I. emelet).

 
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