Thesis supervisor: Norbert Solymosi
Location of studies (in Hungarian): univet.hu Abbreviation of location of studies: ATE
Description of the research topic:
Antimicrobial resistance (AMR) is one of the most significant human and veterinary medical challenges of our time. The genetic basis of AMR is provided by genes (antimicrobial resistance genes, ARGs) and genetic polymorphisms. Improper use of antibiotics results in the selection of bacterial strains harbouring genetic elements that facilitate AMR. These genetic determinants can spread among bacteria through horizontal gene transfer. Some of the ARGs appearing in the human body may come from animals. In these cases veterinary/animal husbandry activity can be blamed for the presence and reproduction of ARGs. A deeper knowledge of how ARGs can get into the human body from animals and animal products may help control this spread.
In the PhD work, we identify substances of the possible pathways of animal-to-human ARG transmission from which samples can be taken. The spectrum of these ARGs will be analysed partly in freely available (NCBI SRA, EBI ENA) datasets and partly in datasets sequenced by our working group.
Required language skills: angol Further requirements: DVM diploma, English language (B2) and computing knowledge. Interest of data mining, programming, bioinformatic and statistical modelling work.
Number of students who can be accepted: 1
Deadline for application: 2021-05-31
2024. IV. 17. ODT ülés Az ODT következő ülésére 2024. június 14-én, pénteken 10.00 órakor kerül sor a Semmelweis Egyetem Szenátusi termében (Bp. Üllői út 26. I. emelet).
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