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Thesis topic proposal
 
Róbert Gáspár
Investigation of the sex differences in metabolism by liver perfusion method

THESIS TOPIC PROPOSAL

Institute: University of Szeged
theoretical medicine
Doctoral School of Multidisciplinary Medical Scienses

Thesis supervisor: Róbert Gáspár
Location of studies (in Hungarian): Dr. Róbert Gáspár, associated professor - Smooth Muscle Research Group, Department of Pharmacology and Pharmacotherapy, Faculty of Medicine, University of Szeged
Abbreviation of location of studies: ÁOK


Description of the research topic:

The drug metabolism is investigated in a newly developed liver perfusion method. The core of the development is that the rat liver is not immersed to liquid as in the traditional perfusion methods, but it placed into a vapor chamber that provides environment more like to the physiological ones. During the experiments the sex difference of given drugs in hepatic metabolism are measured, especially focusing on the sex reassignment-induced alterations, the metabolic consequences of which are barely known. The metabolic changes induced by the sex hormone treatment are investigated in a transgender rat model.

Required language skills: English B2
Number of students who can be accepted: 1

Deadline for application: 2019-08-31


2024. IV. 17.
ODT ülés
Az ODT következő ülésére 2024. június 14-én, pénteken 10.00 órakor kerül sor a Semmelweis Egyetem Szenátusi termében (Bp. Üllői út 26. I. emelet).

 
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