ODT - THESIS TOPIC: Gyöngyi Horváth: Development and comprehensive characterization ...


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Thesis topic proposal

Development and comprehensive characterization of a new, complex schizophrenia rat model by in vivo and in vitro tests

THESIS TOPIC PROPOSAL

Institute: University of Szeged
theoretical medicine
Theoretical Medicine Doctoral School

Thesis supervisor: Gyöngyi Horváth
co-supervisor: Gabriella Kékesi
Location of studies (in Hungarian): University of Szeged, Faculty of Medicine Department of Physiology
Abbreviation of location of studies: PHYS

Description of the research topic:

A new, chronic schizophrenia rat model was developed in our behavior-pharmacological laboratory, named as WISKET rats. The behavioral and electrophysiological studies revealed the translational utility of WISKET rats regarding schizophrenia. Our future proposals are to determine the morphological, receptorial and genetic alterations in WISKET rats by multiple in vitro tests, and further characterize the phenotypic alterations regarding their behavior and autonomic functions. Furthermore, our aims are to determine the predictive validity of the model by antipsychotic administration and to determine the efficacy of additive medications.

Required language skills: english

Deadline for application: 2019-06-30

2024. IV. 17.
ODT ülés
Az ODT következő ülésére 2024. június 14-én, pénteken 10.00 órakor kerül sor a Semmelweis Egyetem Szenátusi termében (Bp. Üllői út 26. I. emelet).