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Thesis topic proposal
 
Sándor Balázs Ötvös
Attila Hunyadi
Preparation of bioactive protoflavone derivatives through selective continuous-flow hydrogenation

THESIS TOPIC PROPOSAL

Institute: University of Szeged
pharmaceutics
Doctoral School of Pharmaceutical Sciences

Thesis supervisor: Attila Hunyadi
co-supervisor: Sándor Balázs Ötvös
Location of studies (in Hungarian): Szeged
Abbreviation of location of studies: SZ


Description of the research topic:

Protoflavonoids, rare natural flavonoids with a non-aromatic B-ring, are valuable model compounds in view of several important pharmacological challenges. Typical cytotoxicity of such compounds, however, limits their potential use. The PhD topic aims the preparation of non-cytotoxic protoflavone derivatives, allowing to explore a new chemical space. The topic combines elements of synthetic chemistry and separation sciences; it includes the preparation of protoflavones and related p-quinols, and their selective, continuous-flow hydrogenation. The work involves intensive international collaboration, hence good English language skills are a must.

Required language skills: fluent english
Number of students who can be accepted: 1

Deadline for application: 2018-06-30


2024. IV. 17.
ODT ülés
Az ODT következő ülésére 2024. június 14-én, pénteken 10.00 órakor kerül sor a Semmelweis Egyetem Szenátusi termében (Bp. Üllői út 26. I. emelet).

 
All rights reserved © 2007, Hungarian Doctoral Council. Doctoral Council registration number at commissioner for data protection: 02003/0001. Program version: 2.2358 ( 2017. X. 31. )