témavezető: Gallyas Ferenc
helyszín (magyar oldal): PTE ÁOK Pécs, Szigeti u. 12. helyszín rövidítés: ÁOK
A kutatási téma leírása:
Oxidative stress is considered as a major pathogenic factor in various diseases. Under pathophysiological conditions macrophages, monocytes and neutrophil granulocytes produce high amounts of reactive oxygen species and various cytokines that can induce cell and tissue damage. These processes occur locally in ischemia-reperfusion related maladies such as cardio- and cerebrovascular diseases, as well as globally in multi organ failure in septic shock. The initiative damaging agents, the reactive oxygen and nitrogen species produced by various processes impair certain intracellular components such as nucleic acids, proteins and lipids. These damages can lead to necrotic or apoptotic cell death by activating specific intracellular signalling pathways. The aim of the PhD project is identifying novel signalling pathway elements or other drug targets that can be used for developing new therapeutic strategies in oxidative stress related diseases.
felvehető hallgatók száma: 1
Jelentkezési határidő: 2020-05-15
2024. IV. 17. ODT ülés Az ODT következő ülésére 2024. június 14-én, pénteken 10.00 órakor kerül sor a Semmelweis Egyetem Szenátusi termében (Bp. Üllői út 26. I. emelet).
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