témavezető: Galajda Péter
helyszín (magyar oldal): Institute of Biophysics, Biological research Centre of the Hungarian Academy of Sciences helyszín rövidítés: SzBK
A kutatási téma leírása:
Bacteria reproduce by binary fission after which two seemingly identical daughter cells are produced. This mode of reproduction raises several questions. Without a clear distinction between “parents” and “daughters”, can the concept of “age” applied to bacteria? Are the daughter cells really identical/similar (phenotypically)? How does (phenotypic) variability emerge in a clonal bacterial population?
During the project we use a novel experimental platform based on optical trapping and microfluidics to study a growing colony with single cell level of detail for an extended period of time. We track cell elongation and division rate, cell survival, expression levels of proteins and swimming behavior in a constantly dividing population of E. coli bacteria. We expect to see how variability and heterogeneity of these measured parameters develop in a clonal population descended from a single cell.
előírt nyelvtudás: angol további elvárások: Expertise in one or more of the following (or related) areas: biology, microbiology, environmental sciences, biophysics, microscopy.
felvehető hallgatók száma: 2
Jelentkezési határidő: 2018-02-28
2024. IV. 17. ODT ülés Az ODT következő ülésére 2024. június 14-én, pénteken 10.00 órakor kerül sor a Semmelweis Egyetem Szenátusi termében (Bp. Üllői út 26. I. emelet).
Bejelentkezés
