témavezető: Szigyártó Imola Csilla
helyszín (magyar oldal): MTA TTK AKI helyszín rövidítés: MTA
A kutatási téma leírása:
Extracellular vesicles (EVs) are biological nanoparticles released by cells into the extracellular space and contain biomolecules (such as DNA, RNA, proteins, phospholipids) that may be characteristic to their cell of origin. They are important mediators of intracellular communication and are involved in many physiological conditions, so they may provide a wealth of information for early diagnosis and treatment of various diseases. With the growing interest in EVs, various isolation techniques have been developed. The efficiency of isolation using density-and size-based isolation methods will be compared. Different bio-physical characterization methods will be used including electron microscopy, dynamic light scattering, protein assays, and spectroscopy methods. In addition, vesicles interactions with drug molecules will be investigated.
előírt nyelvtudás: angol további elvárások: goog synthetic skill, wide interest in structure investigation/separation methods