témavezető: Kiss István
helyszín (magyar oldal): PTE ÁOK Szigeti u. 12. helyszín rövidítés: ÁOK
A kutatási téma leírása:
The so called individual susceptibility factors play an important role in determining the risk of chronic non infectious diseases. These are typically single nucleotide polymorphisms on the area of genes related to cancer development. They are not inherited mutations, but rather normal gene variants, which, however, to a certain extent have an influence on the risk of the formation of different tumours.
In the framework of this PhD topic, allelic distributions (e.g. genes of metabolizing enzymes, DNA repair genes, tumour suppressor genes) are compared between cancer patients and cancer free controls. These molecular epidemiological studies (case-control studies) can lead to the identification of genetic risk factors of certain tumours.
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