Login
 Forum
 
 
Thesis topic proposal
 
The cardiac effects and side effects of pharmacological manipulation of glucose homeostasis

THESIS TOPIC PROPOSAL

Institute: University of Debrecen
general health sciences
Doctoral School of Nutrition and Food Sciences

Thesis supervisor: Dániel Priksz
Location of studies (in Hungarian): DE ÁOK Farmakológiai és Farmakoterápiai Intézet
Abbreviation of location of studies: DEÁOK


Description of the research topic:

In this project, we analyze the pleiotropic effects of novel antidiabetic agents (SGLT-2
inhibitors and glucagon-like peptide analogs) in rodent models, primarily focusing on the
involvement of the cardiovascular system. There is increasing evidence that these pharmacones
not only beneficially influence carbohydrate homeostasis, but also possess cardioprotective
effects, potentially improving cardiac dysfunction resulting from diabetes and obesity, even
more, possibly exerting direct effects on the heart. The compounds are being studied in rodent
models with lipid and carbohydrate metabolism disorders, as well as heart failure, utilizing
state-of-the-art small animal echocardiography and molecular biology techniques.

Required language skills: angol
Number of students who can be accepted: 1

Deadline for application: 2024-05-15


2024. IV. 17.
ODT ülés
Az ODT következő ülésére 2024. június 14-én, pénteken 10.00 órakor kerül sor a Semmelweis Egyetem Szenátusi termében (Bp. Üllői út 26. I. emelet).

 
All rights reserved © 2007, Hungarian Doctoral Council. Doctoral Council registration number at commissioner for data protection: 02003/0001. Program version: 2.2358 ( 2017. X. 31. )