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Thesis topic proposal
 
Mihály Kovács
Molecular mechanisms of genome metabolism and cellular stress response

THESIS TOPIC PROPOSAL

Institute: Eötvös Loránd University, Budapest
biology
Doctoral School of Biology

Thesis supervisor: Mihály Kovács
Location of studies (in Hungarian): ELTE Department of Biochemistry
Abbreviation of location of studies: ELTE


Description of the research topic:

The applicant will perform experimental research in our projects aimed at elucidating how the molecular activities of motor enzymes and associated protein/nucleic acid complexes (single-stranded DNA binding proteins, DNA helicases, myosins) serve the life processes of cell division, reproduction, tissue morphogenesis, regeneration as well as genome stability and metabolic homeostasis. Our further aim is to explore how the pharmacological control of the enzymatic activities and/or condensation properties of the investigated proteins and nucleic acids can be used to aid tissue regeneration and in overcoming the resistance of cancer cells to chemotherapy and that of pathogenic bacteria to antibacterial agents (website: mk-lab.org).

Required language skills: English
Further requirements: 
biochemistry/molecular biology/biophysics/bioinformatics research project experience, fluency in written and spoken English

Number of students who can be accepted: 3

Deadline for application: 2024-05-31

 
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