ODT - THESIS TOPIC: Árpád Dobolyi: The role of the ...


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Thesis topic proposal

The role of the medial prefrontal cortex in the control of social behaviour in rodents

THESIS TOPIC PROPOSAL

Institute: Eötvös Loránd University, Budapest
biology
Doctoral School of Biology

Thesis supervisor: Árpád Dobolyi
co-supervisor: Melinda Vitéz-Cservenák
Location of studies (in Hungarian): ELTE Department of Physiology and Neurobioogy
Abbreviation of location of studies: ELTE

Description of the research topic:

The medial prefrontal cortex (mPFC) plays a crucial role in regulating social behavior in rodents, orchestrating various aspects of social interaction and decision-making. Chemogenetics, a cutting-edge technique, enables researchers to manipulate neuronal activity within specific brain regions like the mPFC, shedding light on its function in social behavior control. By selectively activating or inhibiting neurons in the mPFC using designer receptors exclusively activated by designer drugs (DREADDs), researchers can uncover the causal relationship between mPFC activity and social behavior. Fiber photometry complements chemogenetics by providing real-time monitoring of neuronal activity, allowing for precise correlation between mPFC dynamics and social behavior in rodents.

Required language skills: English
Further requirements:
Biológus OTDK 2. díj

Number of students who can be accepted: 1

Deadline for application: 2024-05-31

2024. IV. 17.
ODT ülés
Az ODT következő ülésére 2024. június 14-én, pénteken 10.00 órakor kerül sor a Semmelweis Egyetem Szenátusi termében (Bp. Üllői út 26. I. emelet).