Thesis supervisor: Imre Varga
Location of studies (in Hungarian): ELTE TTK Abbreviation of location of studies: ELTE
Description of the research topic:
Polymer nanoparticles have played a central role in several recent scientific breakthroughs and are major components in number of newly emerging technologies, ranging from self-healing coatings to drug delivery systems and imaging techniques. Hitherto, such applications have mainly employed polymer nanoparticles with uniform or simple core/shell structures. However, in potential applications (e.g. in therapeutic applications) the polymer nanoparticles have to exhibit complex properties: to be stable, biocompatible, targeted to a specific location, physically and chemically compatible with their cargo and responsive, so that the cargo can be released when required. To meet these challenges there is a compelling need to go beyond simple structures. This project aims at developing hierarchical polymer nanoparticles and 3D structures, with tailored composition and functionalities and controlled responsiveness. These novel hierarchical structures will comprise individual domains/shells with different properties to furnish different functionalities for, e.g., targeted delivery of drug molecules. We will aim at the formation and investigation of two families of hierarchical, soft nanoparticles: pNIPAm microgel and polyelectrolyte complex based hierarchical nanostructures. We will investigate the formation, structure, stability as well as the loading and release characteristics of the prepared particles.
Required language skills: English Number of students who can be accepted: 1
Deadline for application: 2024-05-31
2024. IV. 17. ODT ülés Az ODT következő ülésére 2024. június 14-én, pénteken 10.00 órakor kerül sor a Semmelweis Egyetem Szenátusi termében (Bp. Üllői út 26. I. emelet).
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