Thesis supervisor: Klára Megyeri
Location of studies (in Hungarian): Orvosi Mikrobiológiai és Immunbiológiai Intézet Abbreviation of location of studies: OMI
Description of the research topic:
Cell death subroutines play important role in the pathogenesis of several diseases. Investigation of the features and mechanism of cell demise is of pivotal importance in order to better understand the various disease symptoms and to explore new therapeutic options. We have investigated the effects of rubella virus and herpes simplex virus on apoptosis and autophagy. Our data have suggested that the cytopathogenicity of these viruses is implicated in the development of infections and congenital malformations. We have revealed that bacteria, such as the Propionibacterium acnes also modulate the cellular autophagic process. The pro-autophagic effect of Propionibacterium acnes represents a beneficial mechanism responsible for the maintenance of cutaneous homeostasis. Our present goal is to characterize the cell death subroutines triggered by various bacteria and viruses and to explore the underlying molecular mechanisms.
Required language skills: english Number of students who can be accepted: 1
Deadline for application: 2024-12-31
2024. IV. 17. ODT ülés Az ODT következő ülésére 2024. június 14-én, pénteken 10.00 órakor kerül sor a Semmelweis Egyetem Szenátusi termében (Bp. Üllői út 26. I. emelet).
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