Thesis supervisor: Zsolt Szabó
Location of studies (in Hungarian): Príma Anesztézia Kft. Abbreviation of location of studies: KRÉKF
Description of the research topic:
he ERAS protocol such as „enhanced recovery after surgery” put the minimally invasive
perioperative techniques in new aspect in the last thirty years. It has been proved unequivocally
the lower perioperative surgical stress diminished the number of postoperative complications
and shortened the length of hospital stay.
Video assisted minimal invasive thoracoscopy (VATS) became very often-used technique
worldwide in the last decades. Traditionally positive pressure mechanical ventilation was
performed by double lumen tube (DLT) or by bronchial blocker for the separately ventilated
lungs. Nevertheless, a novel anaesthetic technique, (non-intubated thoracoscopic surgery,
NITS) becomes more and more popular. Anatomical resections, mediastinal tumour mass
resection can be performed by combination of special intravenous and regional anaesthetic
techniques with preserving of spontaneous breathing (1,2).
Many studies presented in the last couple of years and our workgroup’s experience based on
high operations number showed the limitations of NITS (high BMI, intubation difficulties,
diaphragmatic movement, operations required lung isolation) can be solved with new
operational technique called spontaneous breathing with intubation (SVI).(3,4,5)
The first objective of our research program is a comprehensive comparative study of the
oxygen dynamics of the thoracic surgery patients underwent the NITS, VATS and SVI
techniques. Second, in this process, we want to explore the relationship between less surgical
stress caused by the use of minimally invasive techniques and a more favourable perioperative
complication rate.
During our working program comparative test of perioperative, conditions of patients
underwent standard oncological resections with NITS or VATS techniques will be performed
with the following endpoints:
• Postoperative oxygenation and hemodinamics
• Length of hospital stay
• Drainage time and volume of drained fluid
• Visual analogue scale changes(VAS)
• Compilcations
References:
1. Chen KC, Cheng YJ, Hung MH, Tseng YD, Chen JS. Nonintubated thoracoscopic
surgery using regional anesthesia and vagal block and targeted sedation. J Thorac Dis.
2014 Jan;6(1):31–6.
2. Wang B, Ge S. Nonintubated anesthesia for thoracic surgery. J Thorac Dis. 2014
Dec;6(12):1868–74.
3. Furák J, Szabó Z. Spontaneous ventilation combined with double-lumen tube intubation
in thoracic surgery. Gen Thorac Cardiovasc Surg [Internet]. 2021;69(6):976–82.
Available from: https://m2.mtmt.hu/api/publication/31827074
4. Pompeo E, Sorge R, Akopov A, Congregado M, Grodzki T. Non-intubated thoracic
surgery-A survey from the European Society of Thoracic Surgeons. Ann Transl Med.
2015 Mar;3(3):37.
5. Tacconi F, Pompeo E. Non-intubated video-assisted thoracic surgery: Where does
evidence stand? J Thorac Dis. 2016 Apr;8(Suppl 4):S364–75
Required language skills: angol Number of students who can be accepted: 3
Deadline for application: 2024-12-31
2024. IV. 17. ODT ülés Az ODT következő ülésére 2024. június 14-én, pénteken 10.00 órakor kerül sor a Semmelweis Egyetem Szenátusi termében (Bp. Üllői út 26. I. emelet).
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