Thesis supervisor: Diana Mühl
Location of studies (in Hungarian): PTE ÁOK Pécs, Szigeti út 12. Abbreviation of location of studies: ÁOK
Description of the research topic:
Aim: Comparative study on efficacy of haemostatic therapy guided either by standard laboratory parameters or point-of-care testing in patients undergoing vascular surgical procedures. The bleeding risk associated with surgical procedures is increased by the fact that the majority of patients affected are on a single or in some cases on double antiplatelet therapy, and/or receive prolonged anticoagulation treatment. Discontinuation of the treatments is expensive and, in case of indication for acute surgery, may not always be carried out. In the European guidelines, the application of transfusion algorithms and protocols incorporating predefined intervention triggers to guide haemostatic intervention during preoperative bleeding are recommended, as well as viscoelastic point-of-care tests (POCT). The first step for optimal restoration of the function of haemostasis system has to be the regulation of the concentration of fibrinogen in the blood plasma, using either conventional laboratory tests or point-of-care testi. It is essential that besides erythrocyte (RBC) concentrate fresh frozen plasma (FFP) has also to be given (RBC:FFP=2:1) in a timely manner, in a fixed proportion. In case of excessive blood loss and transfusion, administration of thrombocyte concentrate is also necessary.
Number of students who can be accepted: 1
Deadline for application: 2024-05-16
2024. IV. 17. ODT ülés Az ODT következő ülésére 2024. június 14-én, pénteken 10.00 órakor kerül sor a Semmelweis Egyetem Szenátusi termében (Bp. Üllői út 26. I. emelet).
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