ODT - THESIS TOPIC: Dóra Zelena: The role of the ...


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Thesis topic proposal

The role of the corticotropin releasing hormone containing cells of the median raphe in stress regulation

THESIS TOPIC PROPOSAL

Institute: University of Pécs
theoretical medicine
Doctoral School of Basic Medicine

Thesis supervisor: Dóra Zelena
Location of studies (in Hungarian): PTE ÁOK
Abbreviation of location of studies: ÁOK

Description of the research topic:

Corticotropin-secreting hormone (CRH) is the main brain regulator of the stress axis, playing this role primarily from the hypothalamus. Our preliminary studies suggest that CRH is produced in the brainstem, in the median raphe nucleus, and its pharmacogenetic stimulation results in increased stress hormone levels similar to the hypothalamus. Using specific mouse strains and pharmacogenetics, we aim to map the details of this regulation and its contribution to the development of anxiety-depressive disorders.

Number of students who can be accepted: 1

Deadline for application: 2024-05-16

2024. IV. 17.
ODT ülés
Az ODT következő ülésére 2024. június 14-én, pénteken 10.00 órakor kerül sor a Semmelweis Egyetem Szenátusi termében (Bp. Üllői út 26. I. emelet).