ODT - THESIS TOPIC: Dénes Lőrinczy: Conformational changes of skeletal ...


	Login Forum Organisation officers member institutions resolutions (in Hung.) by-laws (in Hung.) regulations Doctoral program doctoral schools by institution by research field by number ceased working academic staff member by name by research topic archives thesis topic proposals by doctoral school by research field by research topic supervision of PhD students search students Theses defended by institution by research field by name by date by doctoral school Naturalized degrees by institution by research field by name by date Habilitation presentations by institution by branch of science by name Documents (all in Hung.) public documents news legal backgrounds guidelines Contacts contact details partners

Thesis topic proposal

Conformational changes of skeletal and cardiac actin/myosin under the effect of toxic agents (phalloidin and jasplaklinolide) and free radicals. A DSC approach

THESIS TOPIC PROPOSAL

Institute: University of Pécs
theoretical medicine
Doctoral School of Interdisciplinary Medical Sciences

Thesis supervisor: Dénes Lőrinczy
Location of studies (in Hungarian): PTE ÁOK Pécs, Szigeti u. 12.
Abbreviation of location of studies: ÁOK

Description of the research topic:

Glycerinated psoas muscle fiber is a good biochemical and mechanical model of the intact muscle. The muscle model and the intermediate states of ATP-hydrolysis cycle depend strongly on the environmental effects. Some of these stabilise the structure (e.g.: toxins) while the free radicals influence the function too through the damage of the structure. UV irradiation of hydrogen peroxide produces free radicals and these will be used to monitor the structural and functional consequences of pathological hydrolysis cycle.

Number of students who can be accepted: 1

Deadline for application: 2024-05-16

2024. IV. 17.
ODT ülés
Az ODT következő ülésére 2024. június 14-én, pénteken 10.00 órakor kerül sor a Semmelweis Egyetem Szenátusi termében (Bp. Üllői út 26. I. emelet).