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Thesis topic proposal
 
Study of the epidemiology, risk factors, clinical presentation and effectiveness of treatment of HPV associated head and neck squamous cell carcinoma (oro-hypopharynx, la

THESIS TOPIC PROPOSAL

Institute: University of Pécs
theoretical medicine
Doctoral School of Pharmacologycal and Pharmaceutical Sciences

Thesis supervisor: István Szanyi
Location of studies (in Hungarian): PTE ÁOK
Abbreviation of location of studies: ÁOK


Description of the research topic:

Head and neck squamous cell carcinoma represents the 6th most common malignant tumour worldwide. The most frequent localisation is the larynx. Smoking and alcohol consumption are important and well known risk factors. However, nowadays the HPV infection is getting more highlight as a serious risk factor in mesopharyngeal cancers, especially involving the tonsils and the base of the tongue. The incidence of the mesopharyngeal squamous cell carcinoma is rising continuously, affecting especially younger men. Although, it's role is emerging also in hypopharyngeal and laryngeal cancers. The most significant difference between the HPV asossiated and non-HPV associated head and neck tumours is the prognosis of the disease. It is known that the HPV associated type correlates with a better prognosis and favorable healing rate. In the treatment of both types is crucial the early diagnosis and starting an adequate treatment without delay. For this purpose, it is inevitably necessary to explore the clinical course, the predisposing factors, the common symptoms of the disease and it's response to the treatment. For this purpose we create a head and neck HPV register.

Number of students who can be accepted: 1

Deadline for application: 2024-05-16


2024. IV. 17.
ODT ülés
Az ODT következő ülésére 2024. június 14-én, pénteken 10.00 órakor kerül sor a Semmelweis Egyetem Szenátusi termében (Bp. Üllői út 26. I. emelet).

 
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