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Thesis topic proposal
 
Máté Varga
Modeling pseudouridylation-related diseases in zebrafish

THESIS TOPIC PROPOSAL

Institute: Eötvös Loránd University, Budapest
biology
Doctoral School of Biology

Thesis supervisor: Máté Varga
Location of studies (in Hungarian): ELTE Eötvös Loránd University, Department of Genetics
Abbreviation of location of studies: ELTE


Description of the research topic:

The successful candidate will characterise already established zebrafish models of monogenic diseases resulting from pseudouridylation defects (mainly Dyskeratosis Congenita). The work will combine state-of-the-art genome editing and sequencing methods with transgenic reporter systems and high-throughput behavioural assays.

Required language skills: English
Further requirements: 
Familiarity with standard molecular experimental systems (molecular cloning, immunostaining, etc.). Previous work experience with zebrafish, knowledge of bioinformatic pipelines used for analysis of next-generation sequencing data, basic Python and R

Number of students who can be accepted: 1

Deadline for application: 2024-05-31


2024. IV. 17.
ODT ülés
Az ODT következő ülésére 2024. június 14-én, pénteken 10.00 órakor kerül sor a Semmelweis Egyetem Szenátusi termében (Bp. Üllői út 26. I. emelet).

 
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