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Thesis topic proposal
 
Péter Kaló
Genetic and functional analysis of genes involved in symbiotic nitrogen fixation

THESIS TOPIC PROPOSAL

Institute: Eötvös Loránd University, Budapest
biology
Doctoral School of Biology

Thesis supervisor: Péter Kaló
co-supervisor: Ágota Domonkos
Location of studies (in Hungarian): HUN-REN Biological Research Centre, Szeged, Temesvári krt. 62 or MATE University, Institute of Genetics and Biotechnology, Gödöllő, Szent-Györgyi A. u. 4
Abbreviation of location of studies: H-REN


Description of the research topic:

Legumes compose the third largest family of flowering plants. Medicago truncatula and other leguminous plants are able to establish nitrogen-fixing symbiotic associations with soil bacteria belonging to the genus rhizobia. The legume-rhizobia symbiosis accounts for a significant proportion of biological nitrogen fixation worldwide. Symbiotic nitrogen fixation takes place in specialized organs on the root, termed nodules. The aim of our research is to study the molecular steps of the invasion and the functioning of the symbiotic nodule to better understand the molecular basis of symbiotic nitrogen fixation. We use plant mutants to analyze the development of the symbiotic nodule. In order to assess the actual function of the genes (Nod or Fix genes) conditioning the mutant phenotype, we plan to clone these genes. The project of the PhD student would be to characterize the symbiotic phenotype of the mutants, identify the impaired genes, characterize their gene products and determine its function in the symbiotic process.

Required language skills: English
Further requirements: 
Good communication skills, Cooperation with other lab members, Basic computer skills

Number of students who can be accepted: 2

Deadline for application: 2024-05-31


2024. IV. 17.
ODT ülés
Az ODT következő ülésére 2024. június 14-én, pénteken 10.00 órakor kerül sor a Semmelweis Egyetem Szenátusi termében (Bp. Üllői út 26. I. emelet).

 
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