Thesis supervisor: Milán Szabó
co-supervisor: Imre Vass
Location of studies (in Hungarian): HUN-REN Biological Research Centre, Institute of Plant Biology Abbreviation of location of studies: SZBK
Description of the research topic:
Symbiodinium is a dinoflagellate alga, which is a photosynthetic partner in coral symbiosis.
This alga is a very important research target due to the coral bleaching phenomenon, which occurs
recently as a consequence of global warming. Despite its importance in aquatic ecosystems, several
physiological mechanisms of this algae remained uncharacterized so far, because of the lack of
efficient transformation methods. In the project we aim to develop a transformation system for the
nuclear genes of Symbiodinium, by using a microfluidic approach to create protoplasts from
Symbiodinium cells, which are able to take up oligonucleotides that can be used for the
transformation of nuclear genes. With this unique approach, resulting in loss of function of targeted
genes and processes we aim to characterize photosynthetic processes in Symbiodinium on single cell
level. With this approach we aim to establish a single cell phenotyping system of Symbiodinium sp. in
order to gain more insights into the photoprotective mechanisms that help to avoid coral bleaching.
Required language skills: reading scientific papers in E Recommended language skills (in Hungarian): sci. comm. in English Further requirements: dedication to scientific work
Number of students who can be accepted: 2
Deadline for application: 2024-08-31
2024. IV. 17. ODT ülés Az ODT következő ülésére 2024. június 14-én, pénteken 10.00 órakor kerül sor a Semmelweis Egyetem Szenátusi termében (Bp. Üllői út 26. I. emelet).
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