ODT - THESIS TOPIC: István Szatmári: Synthesis and transformations of ...


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Thesis topic proposal

Synthesis and transformations of bioactive KYNA derivatives

THESIS TOPIC PROPOSAL

Institute: University of Szeged
pharmaceutics
Doctoral School of Pharmaceutical Sciences

Thesis supervisor: István Szatmári
co-supervisor: Bálint Lőrinczi
Location of studies (in Hungarian): Szeged
Abbreviation of location of studies: SZTE

Description of the research topic:

It has previously proved that 4-hydroxyquinoline-2-carboxylic acid (KYNA) is a neuroprotective agent. In frame of the previous researches in the Institute of Pharmaceutical Chemistry, the penetration of KYNA derivatives together with their solubility has been increased by insertion of different substituents on the KYNA skeleton. The potential in this research field is to investigate new KYNA derivatives by which the penetration might be further increased and at the same time their biological activity might also be improved

Required language skills: fluent english
Recommended language skills (in Hungarian): fluent english
Number of students who can be accepted: 1

Deadline for application: 2024-08-31

2024. IV. 17.
ODT ülés
Az ODT következő ülésére 2024. június 14-én, pénteken 10.00 órakor kerül sor a Semmelweis Egyetem Szenátusi termében (Bp. Üllői út 26. I. emelet).