Thesis supervisor: Anikó Keller-Pintér
co-supervisor: László Rovó
Location of studies (in Hungarian): SZTE SZAOK Biokémiai Intézet Abbreviation of location of studies: SZTE
Description of the research topic:
Atrophy of the skeletal muscle fibres that form the vocal folds can be caused by, among other things, vocal fold paralysis, and can also occur during ageing. The main symptom of vocal fold atrophy, apart from hoarseness, is breathing difficulties. In today's ageing society, vocal fold atrophy caused by sarcopenia is a growing problem. Our work aims to find new therapeutic options to increase the muscle volume of atrophied vocal folds. First, we will investigate the effects of the different drugs on differentiated myotubes in vitro using molecular and cell biological methods, and then we will study the effects on muscle size in an in vivo animal model. Importantly, increasing denervated muscle volume is of therapeutic importance due to the biomechanical properties of the larynx without restoring innervation
Required language skills: English Further requirements: research work
Number of students who can be accepted: 1
Deadline for application: 2024-05-31
2024. IV. 17. ODT ülés Az ODT következő ülésére 2024. június 14-én, pénteken 10.00 órakor kerül sor a Semmelweis Egyetem Szenátusi termében (Bp. Üllői út 26. I. emelet).
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