Thesis supervisor: Mária Dux
Location of studies (in Hungarian): SZAOK Élettani Intézet Abbreviation of location of studies: SZAOK
Description of the research topic:
Peripheral and central sensitization of the trigeminal pathway plays significant role in the pathophysiology of migraine pain. Activation or sensitization of the trigeminal primary sensory neurons innervating the intra- and extracranial tissues plays central role in both mechanisms. Local inflammatory reactions of the innervated meningeal tissue or systemic conditions e.g. obesity may increase the sensitivity of neurons that may result in an increase of frequency or severity of headache attacks. In our experiments we study in animal models the pathophysiological changes and possible therapeutic interventions that may alter the sensitivity of the trigeminal pathway and have relevance for the treatment of migraine headache.
Required language skills: English Number of students who can be accepted: 3
Deadline for application: 2024-03-31
2024. IV. 17. ODT ülés Az ODT következő ülésére 2024. június 14-én, pénteken 10.00 órakor kerül sor a Semmelweis Egyetem Szenátusi termében (Bp. Üllői út 26. I. emelet).
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