Thesis supervisor: István Wittmann
Location of studies (in Hungarian): PTE ÁOK Pécs, Szigeti u. 12. Abbreviation of location of studies: ÁOK
Description of the research topic:
We plan the investigation of following hypotheses:
1. Phosphorylation of eNOS changes upon cigarette smoke in 3T3-L1 adipocytes. Western blot studies. 2. Examination of phosphorylation of Akt using Western blot in 3T3-L1 adipocytes due to oxidative stress. 3. Examination of phosphorylation of Erk in 3T3-L1 adipocytes due to oxidative stress using Western blot. 4. To study the effect of antioxidant resveratrol on the signaling pathways of insulin and erythropoietin using Western blot. 5. To study the connection between carbohydrate metabolism and oxidative stress using continuous interstitial glucose monitoring (CGMS) and measurement of oxidative stress. 6. Measurement of hydrogen-peroxide in vivo with a sensor in development.