Thesis supervisor: Tamás Simor
co-supervisor: Réka Faludi
Location of studies (in Hungarian): PTE ÁOK Pécs, Szigeti út 12. Abbreviation of location of studies: ÁOK
Description of the research topic:
The roles of the atria are more complicated than we expected before and far from being a simple passive transport to the chambers. They are responding to pressure and stretch with the secretion of atrial natriuretic peptides (ANP) to counterbalance the sympathetic and renin-angiotensin-aldosterone systems allowing partial restoration of fluid and haemodynamic balance. Enlargement of the atria have been shown to be a reliable predictor of adverse cardiovascular outcomes, such as atrial fibrillation and remodelling. Our understanding of atrial function is rapidly evolving, and data are accumulating to suggest that this is a powerful biomarker for atrial fibrillation and heart failure. There have been huge advances in terms of our ability to characterize and quantitate atrial function using non-invasive imaging. MRI is the gold standard to evaluate the atrial function, but as an advantage to the echocardiography, it is widely used and more easily performed in the clinical practice. There are several methods in echocardiography, such as volumetric measurements which is the closest to the technique of the MRI assessments and the speckle tracking based strain. We have to find out which method of atrial function assessment is essential to its clinical and research applications. Thus we aimed to investigate the correlation between echocardiograpic and valid CMR-derived parameters. Understanding the former questions will enable the development of more effective strategies for the treatment and prevention of atrial fibrillation, heart failure, and stroke.
Number of students who can be accepted: 1
Deadline for application: 2023-05-19
2024. IV. 17. ODT ülés Az ODT következő ülésére 2024. június 14-én, pénteken 10.00 órakor kerül sor a Semmelweis Egyetem Szenátusi termében (Bp. Üllői út 26. I. emelet).
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