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Thesis topic proposal
 
Csaba András Dézsi
Changes in plasma levels of bioactive peptides during acute myocardial infarction

THESIS TOPIC PROPOSAL

Institute: University of Pécs
clinical medicine
Doctoral School of Clinical Medicine

Thesis supervisor: Csaba András Dézsi
Location of studies (in Hungarian): PTE ÁOK Pécs, Szigeti u. 12.
Abbreviation of location of studies: ÁOK


Description of the research topic:

The initiation and progression of atherosclerosis in coronary arteries, the destabilisation of culprit lesion, the rupture of the coronary plaque, and the eventual development of myocardial infarction are complex multifactorial processes. We have considerable knowledge about the basics of cellular and molecular mechanisms related to it. It has been justified in connection with several classical risk factors that in the pathophysiological background of their damaging effect on arteries we can find immunopathological reactions triggered by them. They cause endothelial dysfunction which contributes to atherosclerosis. During our research, we would like to characterize the change in the plasma levels of pro- and anti-inflammatory cytokines, chemokines involved in the process during different types of acute myocardial infarction (STEMI, NSTEMI). We investigate whether some plasma levels are likely to predict the development of left ventricular function and the likelihood of cardiovascular mortality in the long term.

Number of students who can be accepted: 1

Deadline for application: 2023-05-19


2024. IV. 17.
ODT ülés
Az ODT következő ülésére 2024. június 14-én, pénteken 10.00 órakor kerül sor a Semmelweis Egyetem Szenátusi termében (Bp. Üllői út 26. I. emelet).

 
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