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Thesis topic proposal
 
New opportunities, MRI biomarkers in the evaluation of head and neck cancer

THESIS TOPIC PROPOSAL

Institute: University of Pécs
clinical medicine
Doctoral School of Clinical Medicine

Thesis supervisor: Mária Gődény
Location of studies (in Hungarian): PTE ÁOK Pécs, Szigeti u. 12.
Abbreviation of location of studies: ÁOK


Description of the research topic:

Magnetic Resonance Imaging (MRI) has developed rapidly during the past few years, which according to the needs of therapy, has opened new perspectives in oncologic head and neck imaging with better realization of the latest technological advances. New therapeutic methods (improvement of radiation therapy and chemotherapy) need better tumor characterization and prognostic information along with the most accurate anatomical information. Multiparametric and multimodal anatomical and functional MR imaging (MM-MRI) using high magnetic field strength (3Tesla) are useful in determining tumour-specific MRI biomarkers and in evaluating the qualitative and quantitative changes in these parameters during therapy to provide assessment of the therapeutic response. Diffusion-weighted MRI (DW-MRI) – provides information at the cellular level about the cell density and the integrity of the plasma membrane. Dynamic contrast-enhanced MRI (DCE-MRI), as a marker of angiogenesis – provides information about vascularisation at the tissue level. Magnetic resonance spectroscopic imaging (MRSI) – provides biochemical analysis at the molecular level.

Number of students who can be accepted: 1

Deadline for application: 2023-05-19


2024. IV. 17.
ODT ülés
Az ODT következő ülésére 2024. június 14-én, pénteken 10.00 órakor kerül sor a Semmelweis Egyetem Szenátusi termében (Bp. Üllői út 26. I. emelet).

 
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