Thesis topic proposal
Edina Szabó-Meleg
Investigation of the formation and function of membrane nanotubes as direct intercellular communication pathways


Institute: University of Pécs
theoretical medicine
Doctoral School of Interdisciplinary Medical Sciences

Thesis supervisor: Edina Szabó-Meleg
Location of studies (in Hungarian): PTE ÁOK Pécs, Szigeti u. 12.
Abbreviation of location of studies: ÁOK

Description of the research topic:

Membrane nanotubes are long, temporary membrane protrusions, providing more than physical connections between cells. Membrane nanotubes are described as direct communication pathways between certain cells (T-lymphocyte, neuran cells, kidney cells, myeloid cells, some cancer cells) transporting different matters or chemical signals. In the last few years nanotubes have quickly gained interest demonstrating a capability of spreading diseases among cells avoiding activation of the immune system. Viruses, prions, different cell organelles, membrane surface proteins, lipids have been identified to migrate between cells using membrane nanotubes. Our aim is to reveal molecular processes and interactions in the formation and function of membrane nanotubes.

Number of students who can be accepted: 1

Deadline for application: 2023-05-19

All rights reserved © 2007, Hungarian Doctoral Council. Doctoral Council registration number at commissioner for data protection: 02003/0001. Program version: 2.2358 ( 2017. X. 31. )