Thesis topic proposal
Péter Hegyi
Áron Vincze
The epidemiology of precancerous pathologies and cancers in the upper gastrointestinal tract in Eastern Europe


Institute: University of Pécs
theoretical medicine
Doctoral School of Pharmacologycal and Pharmaceutical Sciences

Thesis supervisor: Áron Vincze
co-supervisor: Péter Hegyi
Location of studies (in Hungarian): PTE ÁOK Pécs, Szigeti u. 12.
Abbreviation of location of studies: ÁOK

Description of the research topic:

The aim of this research is to gather epidemiological data on on the precancerous pathologies and cancers of the UGI tract and to better understand the geographical differences of these pathologies between Eastern Europe and the rest of the World. Recent significant technical and scientific advances resulted in the development of effective endoscopic treatment for early neoplasia in the UGI tract and there is ample data and research in this topic in Western Europe, North America, Australia and the developed countries of Asia, however there is very little known about the epidemiology of these pathologies in Eastern Europe and there is very scarce data on the treatment of these conditions.
The main areas for research and work will be:
The epidemiological trends of squamous cell cancer and adenocarcinoma of the oesophagus and gastric cancer in the last five decades in Eastern Europe.
The epidemiology of H. pylori in Eastern Europe since its discovery.
Investigation of the relationship between the above two epidemiological trends and findings.
The epidemiology of precancerous pathologies in the UGI tract (Barrett's oesophagus and chronic atrophic gastritis) in Eastern Europe.
Building prospective registries and databases for the above pathologies.
Initiation of international cooperation in the above scientific research.
This scientific project is the essential first step in organising and advancing the Hungarian endoscopic service for precancerous pathologies and early neoplasia in the UGI tract.

Number of students who can be accepted: 1

Deadline for application: 2023-05-17

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