Thesis topic proposal
Generation and characterization of complement activation inhibiting proteins


Institute: Eötvös Loránd University, Budapest
Doctoral School of Biology

Thesis supervisor: Mihály Krisztián Józsi
Location of studies (in Hungarian): ELTE TTK Institute of Biology, Department of Immunology
Abbreviation of location of studies: ELTE

Description of the research topic:

The complement system is an importent component of innate immunity. Complement dysfunction and dysregulation, however, may lead various diseases and damage to the host. Inhibitors acting at certain points of the complement activation routes could have therapeutic potential in the treatment of complement-mediated diseases. The PhD candidate, therefore, is expected to generate and characterize complement inhibiting proteins, and compare their activity with complement factor H and other complement inhibiting molecules.

Required language skills: English
Further requirements: 
Further requirements: excellent study record, independent thinking, proactive approach, excellent laboratory (manual) skills

Number of students who can be accepted: 1

Deadline for application: 2023-05-31

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