Thesis supervisor: Tamás Szabó
Location of studies (in Hungarian): University of Szeged, Department of Physical Chemistry and Materials Science Abbreviation of location of studies: FKAT
Description of the research topic:
This research is directed towards the synthesis of magnetically modified composites involving graphene oxide (GO) and related graphene based materials, along with superparamagnetic iron oxide nanoparticles (SPIO-NP) with a focus on a potential biomedical application (magnetic thermotherapy and controlled drug release).
- Our first aim is to formulate colloidal dispersions of the aforementioned materials, which retain their stability in biorelevant media.
- Optimized synthesis conditions of SPIO particles and GO (reduced GO, RGO) lamellae are expected to lead to nanocomposites of enhanced hyperthermic efficiency towards the selective attack of malignant tumors.
- We also intend to investigate the potential of these single-phase and composite materials as nanocarriers in drug delivery, considering the pH-sensitive surface charge and colossal surface area of GO particles and the magnetically controllable transport and heat production of SPIO-NPs
- We foresee that the biointercalated GO nanocomposites enable for (i) the increase of drug loading compared to traditional carriers based on the adsorption capacity, (ii) chemically controlled release for cationic drugs.
Number of students who can be accepted: 1
Deadline for application: 2022-08-31
2024. IV. 17. ODT ülés Az ODT következő ülésére 2024. június 14-én, pénteken 10.00 órakor kerül sor a Semmelweis Egyetem Szenátusi termében (Bp. Üllői út 26. I. emelet).