Thesis supervisor: Roland Patai
Location of studies (in Hungarian): Biological Research Centre, Szeged department of Biophysics Abbreviation of location of studies: BRC
Description of the research topic:
Glial cells – one of the most abundant cells in the central nervous system – have got a crucial role both in the physiological and pathological processes. The importance of these cells is well-known in numerous neurodegenerative diseases e.g., in Parkinson’s disease and Alzheimer’s disease, and even in traumatic brain and spinal cord injury. However, further investigation is needed on their degenerative and regenerative role and on the molecular machinery behind these processes in motor neuron degeneration. Our main objective is to determine the spatiotemporal roles of glial cells – astrocyte and microglia, particularly – and their changes in animal models of chronic and acute motoneuron diseases. For this purpose, our experiments using morphology, morphometry, and other pharmacological and molecular biological methods. Our goal is to find appropriate therapeutic agents to modify the neuronal milieu which promoting regeneration and functional recovery.
Required language skills: english
Deadline for application: 2022-06-30
2024. IV. 17. ODT ülés Az ODT következő ülésére 2024. június 14-én, pénteken 10.00 órakor kerül sor a Semmelweis Egyetem Szenátusi termében (Bp. Üllői út 26. I. emelet).
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