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Thesis topic proposal
 
László Lénárd
Importance of hedonic evaluation of food reward: animal experiments and human examinations

THESIS TOPIC PROPOSAL

Institute: University of Pécs
theoretical medicine
Doctoral School of Basic Medicine

Thesis supervisor: László Lénárd
Location of studies (in Hungarian): PTE ÁOK Pécs, Szigeti u. 12.
Abbreviation of location of studies: ÁOK


Description of the research topic:

The hunger motivated behavior is based on the integration of homeostatic endogenous humoral and neural information and of exogenous food related cues signaling the availability of food reward. In case of feeding disorders (obesity, anorexia, bulimia) effects of hedonic evaluation of foods and liquids, evaluation of the smell, taste, texture and sight of different foods, as well as the effects of social factors (ideal body shape) are extremely important. In animal experiments learning mechanisms of taste preference and conditioned taste aversion will be examined by means of neurochemical, electrophysiological and behavioral methods. In acute and chronic experiments single neuronal activity will be examined in the limbic system and prefrontal cortex during neophobia, application of different taste solutions and during changes of reward quality of foods. Ingestive and rejective mimetic responses will be examined by means of behavioral methods. In the second part of the project human examinations will be executed in patients with obesity and anorexia nervosa. After completing appropriate neuropsychological tests fMRI examinations will be made.

Number of students who can be accepted: 1

Deadline for application: 2022-05-20


2024. IV. 17.
ODT ülés
Az ODT következő ülésére 2024. június 14-én, pénteken 10.00 órakor kerül sor a Semmelweis Egyetem Szenátusi termében (Bp. Üllői út 26. I. emelet).

 
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