Thesis supervisor: Krisztián Kvell
Location of studies (in Hungarian): PTE ÁOK Pécs, Szigeti u. 12. Abbreviation of location of studies: ÁOK
Description of the research topic:
Thymic senescence is defined by the degeneration or adipose involution of the thymic epithelium. The process begins rather early in life, right after puberty. The process leads to decreased naive T-cell production with severe immunological consequences (increased incidence of infections, autoimmune diseases and cancers). PPARgamma has a key role in the process and its biochemical role and partners are currently being discovered. These challenging discoveries have significant medical relevance.
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