Thesis supervisor: Csaba Hetényi
Location of studies (in Hungarian): PTE ÁOK Pécs, Szigeti u. 12. Abbreviation of location of studies: ÁOK
Description of the research topic:
Signal transduction is a key to understanding pathomechamisms of various diseases. Signaling pathways are often based on the formation of complexes between protein partners. In many cases, experimental determination of atomic resolution structures of protein complexes (required by drug design) is difficult. In the present project, we will calculate the structure of such complexes using computational tools. We will also study their molecular dynamics to understand their role in signaling and provide starting information for drug development.