Thesis topic proposal
Milán Szőri
Passive Transport Phenomena of Pollutes on Biomembranes


Institute: University of Miskolc
material sciences
Antal Kerpely Doctoral School of Materials Science and Technology

Thesis supervisor: Milán Szőri
Location of studies (in Hungarian): ME-MAK-KI
Abbreviation of location of studies: MAK

Description of the research topic:

The understanding of the passive membrane permeation is crucial to gain insight into mechanism of action, disposition, toxicity of pollutants. Passive diffusion is the main limitation of penetration of small pollutant molecules and thus the main barrier for their infiltration into living cells. This phenomenon can be understood based on free energy calculations using metadynamic technique. By means of atomistic modeling, the changes in the membrane structure and the required energy for the transport can be determined. The aim of the project is to determine the energy barrier of the passive transport of a set of pesticides and pollutants in order to identify the key molecular features of fast transport. With these features in hand, prediction of the environmental hazard can be made.

Required language skills: English
Number of students who can be accepted: 1

Deadline for application: 2022-01-15

All rights reserved © 2007, Hungarian Doctoral Council. Doctoral Council registration number at commissioner for data protection: 02003/0001. Program version: 2.2358 ( 2017. X. 31. )