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Thesis topic proposal
 
Bioinformatic developments for the analysis of next-generation sequencing data

THESIS TOPIC PROPOSAL

Institute: University of Szeged
biology
Doctoral School of Biology

Thesis supervisor: Lajos Haracska
Location of studies (in Hungarian): ELKH, Biological Research Center
Abbreviation of location of studies: SZBK


Description of the research topic:

One of the fastest evolving fields of biology is next-generation sequencing (NGS). NGS procedures are capable of generating a significant amount of genomic data in a cost-efficient way. Though general bioinformatic methods have already been implemented, the adaptation of these to different sample preparation methods requires new development. Such a development is the introduction of unique molecular counters via which every single original piece of DNA is linked with a unique molecular counter, thus, by identifying these, later the original amount of templates can be determined precisely, independently of the amplification steps. Molecular counters help reduce faults during library preparation. The topic involves working on developments related to all currently available NGS methods (ChIP-Seq, RNA seq, Metagenom, Single cell techniques).

Required language skills: English
Recommended language skills (in Hungarian): English
Further requirements: 
A grade average above 4.0, participation at TDK or other competititons, lab experience.

Number of students who can be accepted: 5

Deadline for application: 2021-09-01


2024. IV. 17.
ODT ülés
Az ODT következő ülésére 2024. június 14-én, pénteken 10.00 órakor kerül sor a Semmelweis Egyetem Szenátusi termében (Bp. Üllői út 26. I. emelet).

 
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