Thesis supervisor: Lajos Haracska
Location of studies (in Hungarian): ELKH, Biological Research Center Abbreviation of location of studies: SZBK
Description of the research topic:
Non-invasive genetic diagnostics, or liquid biopsy, is based on the analysis of DNA or RNA isolated from the cell-free fraction of the blood. The term includes molecular diagnostic procedures that monitor different changes in the organism by sequencing and quantitating circulating cell-free nucleic acids. Currently, these types of methods represent the fastest evolving field in the precise diagnostics and characterisation of tumorous diseases and foetal genetic disorders. From a diagnostic point of view, the common characteristic of these two conditions is that the wild-type background derived from the tumour or the foetus is in great excess in the otherwise very limited amount of genetic material in the blood plasma.
Our research group works on developing panels with which the most frequent alterations found in certain diseases can be analysed via the next-generation sequencing of specific targeted regions.
Required language skills: English Recommended language skills (in Hungarian): English Further requirements: A grade average above 4.0, participation at TDK or other competititons, lab experience.
Number of students who can be accepted: 5
Deadline for application: 2021-09-01
2024. IV. 17. ODT ülés Az ODT következő ülésére 2024. június 14-én, pénteken 10.00 órakor kerül sor a Semmelweis Egyetem Szenátusi termében (Bp. Üllői út 26. I. emelet).
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