Thesis supervisor: Péter Hegyi
co-supervisor: Andrea Ildikó Szentesi
Location of studies (in Hungarian): SZTE ÁOK I. Sz. Belgyógyászati Klinika Abbreviation of location of studies: IBEL
Description of the research topic:
On the morning of March 12, 2020, the World Health Organization (WHO) announced the outbreak of the new coronavirus disease (COVID-2019). By the time this research proposal was written, more than 3,500,000 cases had been confirmed from more than 180 countries, claiming the lives of more than half a million people. This trend predicts that the epidemic is still far from peaking. As with other infectious diseases, some cases are asymptomatic or mild, so they remain undiagnosed. Thus, it is difficult to accurately estimate the true incidence and outcome of the disease. An analysis of 72,314 Chinese patients with the SARS CoV-2 epidemic found that 5% of the population required intensive care (ICU), with the most common indications being acute respiratory failure, septic shock, and / or multiple organ failure. Similar data were reported from Italy. Two days after the outbreak in Italy, 60% of the ICU beds in the Lombardy region was occupied by COVID-19 patients. The situation that has since deteriorated significantly. We are launching several research projects that study (1) the pathomechanism of the disease course, (2) the disease-aggravating comorbidities, and (3) the disease course characteristics. ETT TUKEB Ethical approval number: 20800-6/2020 EÜIG.