ODT - THESIS TOPIC: László Kollár: Amino-functionalized skeletons of practical ...


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Thesis topic proposal

Amino-functionalized skeletons of practical importance used as N-nucleophiles in aminocarbonylation

THESIS TOPIC PROPOSAL

Institute: University of Pécs
chemistry
Doctoral School of Chemistry

Thesis supervisor: László Kollár
Location of studies (in Hungarian): University of Pécs, Faculty of Sciences, Institute of Chemistry
Abbreviation of location of studies: PTE

Description of the research topic:

Palladium-catalysed aminocarbonylation can efficiently be used for the acylation of primary and secondary amines possessing more complicated structures. In other words, the above amines are used as N-nucleophiles in aminocarbonylation of simple iodoalkenes and iodoaromatics. In this way, aminosteroids and further polycyclic aminoterpenes, as well as alkaloids are planned to be used. According to previous studies, the formation of carboxamides and 2-ketocarboxamides are expected.
The application of environmentally benign conditions (carbon monoxide-free reactions, alternative solvents) will be studied.

Required language skills: english
Number of students who can be accepted: 1

Deadline for application: 2021-01-15

2024. IV. 17.
ODT ülés
Az ODT következő ülésére 2024. június 14-én, pénteken 10.00 órakor kerül sor a Semmelweis Egyetem Szenátusi termében (Bp. Üllői út 26. I. emelet).